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Characterization of a monoclonal antibody directed against the biologically active site of human interleukin 1

Human IL-1 was successfully used to produce an anti-IL-1 mAb. Anti-IL-1 (IgG2a) blocked IL-1-mediated thymocyte and fibroblast proliferation, but did not interfere with the biological effects of other lymphokines, such as IL-2 or IL-3. The antibody immunoprecipitated biosynthetically radiolabeled 33...

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Bibliografski detalji
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 1986
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2188039/
https://ncbi.nlm.nih.gov/pubmed/2418147
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