Characterization of a novel inhibitory human monoclonal antibody directed against Plasmodium falciparum Apical Membrane Antigen 1

Malaria remains a major challenge to global health causing extensive morbidity and mortality. Yet, there is no efficient vaccine and the immune response remains incompletely understood. Apical Membrane Antigen 1 (AMA1), a leading vaccine candidate, plays a key role during merozoite invasion into ery...

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Vydáno v:Sci Rep
Hlavní autoři: Maskus, Dominika J., Królik, Michał, Bethke, Susanne, Spiegel, Holger, Kapelski, Stephanie, Seidel, Melanie, Addai-Mensah, Otchere, Reimann, Andreas, Klockenbring, Torsten, Barth, Stefan, Fischer, Rainer, Fendel, Rolf
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5175200/
https://ncbi.nlm.nih.gov/pubmed/28000709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39462
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