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GABA uptake into astrocytes is not associated with significant metabolic cost: Implications for brain imaging of inhibitory transmission

Synaptically released glutamate has been identified as a signal coupling excitatory neuronal activity to increased glucose utilization. The proposed mechanism of this coupling involves glutamate uptake into astrocytes resulting in increased intracellular Na(+) (Na(i)(+)) and activation of the Na(+)/...

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Bibliografiske detaljer
Main Authors: Chatton, Jean-Yves, Pellerin, Luc, Magistretti, Pierre J.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC218779/
https://ncbi.nlm.nih.gov/pubmed/14530410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2132096100
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