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Characterization of binding and biological effects of monoclonal antibodies against a human tumor necrosis factor receptor

Three different antibodies against a human TNF receptor (htr-1, htr-5, and htr-9) have been examined for their binding pattern to U937 cells and ability to mimic TNF-alpha activity in U937 cells, Fs4 fibroblasts, and human endothelial cells. Flow cytometric analysis revealed that htr- 5 and htr-9 bo...

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Bibliographic Details
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1990
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2187730/
https://ncbi.nlm.nih.gov/pubmed/1689365
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