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Preferential linkage of bcl-2 to immunoglobulin light chain gene in chronic lymphocytic leukemia

Most of human follicular lymphomas possess the t(14;18) chromosome translocation that juxtaposes the IgH gene to the 3' region of bcl-2 in a head-to-tail configuration. Here we show that the rearrangement of the bcl-2 gene occurs in a significant fraction (approximately of 10%) of B cell CLL. I...

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Bibliographische Detailangaben
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 1990
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2187727/
https://ncbi.nlm.nih.gov/pubmed/2106002
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