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Anti-neutrophil cytoplasm antibodies in Wegener's granulomatosis recognize an elastinolytic enzyme

The target antigen of anti-neutrophil cytoplasm antibodies (ACPA; also known as ANCA) was isolated by affinity chromatography from supernatants of human neutrophils, stimulated with phorbol ester to induce degranulation. Sequence analysis of the antigen revealed 17 NH2- terminal amino acids (IVGGHEA...

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Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 1990
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2187669/
https://ncbi.nlm.nih.gov/pubmed/1688612
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