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Single-cell analysis of covalently closed circular DNA copy numbers in a hepadnavirus-infected liver

Hepatitis B virus (hepadnavirus) infections are maintained by the presence of a small and regulated number of episomal viral genomes [covalently closed circular DNA (cccDNA)] in the nuclei of infected cells. Although a number of studies have measured the mean copy number of cccDNA molecules in hepad...

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Main Authors: Zhang, Yong-Yuan, Zhang, Bai-Hua, Theele, Daniel, Litwin, Samuel, Toll, Eugene, Summers, Jesse
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2003
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC218765/
https://ncbi.nlm.nih.gov/pubmed/14528003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2033898100
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