Establishment of memory for IL-10 expression in developing T helper 2 cells requires repetitive IL-4 costimulation and does not impair proliferation

T helper (Th) lymphocytes can develop memory for the expression of particular cytokines, like IL-4 or IL-10, in that reexpression of those cytokines is independent of the original costimulatory signal IL-4 and depends only on T cell receptor stimulation. Here, we show that in the course of Th2 cell...

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Bibliographic Details
Main Authors: Löhning, Max, Richter, Anne, Stamm, Torsten, Hu-Li, Jane, Assenmacher, Mario, Paul, William E., Radbruch, Andreas
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2003
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC218754/
https://ncbi.nlm.nih.gov/pubmed/14514890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2035254100
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