Insights into peptide nucleic acid (PNA) structural features: The crystal structure of a d-lysine-based chiral PNA–DNA duplex

Peptide nucleic acids (PNAs) are oligonucleotide analogues in which the sugar-phosphate backbone has been replaced by a pseudopeptide skeleton. They bind DNA and RNA with high specificity and selectivity, leading to PNA–RNA and PNA–DNA hybrids more stable than the corresponding nucleic acid complexe...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Principais autores:	Menchise, Valeria, De Simone, Giuseppina, Tedeschi, Tullia, Corradini, Roberto, Sforza, Stefano, Marchelli, Rosangela, Capasso, Domenica, Saviano, Michele, Pedone, Carlo
Formato:	Artigo
Idioma:	Inglês
Publicado:	National Academy of Sciences 2003
Assuntos:	Biological Sciences
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC218706/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14512516/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.2034746100
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