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Insights into peptide nucleic acid (PNA) structural features: The crystal structure of a d-lysine-based chiral PNA–DNA duplex

Peptide nucleic acids (PNAs) are oligonucleotide analogues in which the sugar-phosphate backbone has been replaced by a pseudopeptide skeleton. They bind DNA and RNA with high specificity and selectivity, leading to PNA–RNA and PNA–DNA hybrids more stable than the corresponding nucleic acid complexe...

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Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Menchise, Valeria, De Simone, Giuseppina, Tedeschi, Tullia, Corradini, Roberto, Sforza, Stefano, Marchelli, Rosangela, Capasso, Domenica, Saviano, Michele, Pedone, Carlo
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2003
Teme:
Biological Sciences
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC218706/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14512516/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.2034746100
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