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Anti-cell surface pemphigus autoantibody stimulates plasminogen activator activity of human epidermal cells. A mechanism for the loss of epidermal cohesion and blister formation

Binding of anti-cell surface pemphigus autoantibodies to cultured human epidermal cells stimulates synthesis and secretion of plasminogen activator (PA). Increases in PA activity were detected within 6 h of the addition of IgG and stimulation was dependent upon IgG concentration. Stimulation of PA a...

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Bibliographic Details
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1983
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2186905/
https://ncbi.nlm.nih.gov/pubmed/6681540
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