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Oxidative stress and inflammation in iron-overloaded patients with β-thalassaemia or sickle cell disease

Blood transfusion therapy is life-saving for patients with β-thalassaemia and sickle cell disease (SCD), but often results in severe iron overload. This pilot study examined whether the biomarkers of tissue injury or inflammation differ in these two diseases. Plasma malondialdehyde (MDA) was signifi...

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Bibliographic Details
Main Authors: Walter, Patrick B., Fung, Ellen B., Killilea, David W., Jiang, Qing, Hudes, Mark, Madden, Jacqueline, Porter, John, Evans, Patricia, Vichinsky, Elliott, Harmatz, Paul
Format: Artigo
Language:Inglês
Published: 2006
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2185791/
https://ncbi.nlm.nih.gov/pubmed/17010049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2141.2006.06277.x
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