Increased leucocyte apoptosis in transfused β-thalassaemia patients

This exploratory study assessed apoptosis in peripheral blood leucocytes (PBL) from β-thalassaemia patients receiving chronic transfusions and chelation therapy (deferasirox or deferoxamine) at baseline, 1, 6, and 12 months. At baseline, thalassaemic PBLs presented 50% greater levels of Bax (BAX), 7...

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Pubblicato in:Br J Haematol
Autori principali: Walter, Patrick B., Porter, John, Evans, Patricia, Kwiatkowski, Janet L., Neufeld, Ellis J., Coates, Thomas, Giardina, Patricia J., Grady, Robert W., Vichinsky, Elliott, Olivieri, Nancy, Trachtenberg, Felicia, Alberti, Daniele, Fung, Ellen, Ames, Bruce, Higa, Annie, Harmatz, Paul
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4597914/
https://ncbi.nlm.nih.gov/pubmed/23216540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bjh.12076
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