Increased leucocyte apoptosis in transfused β-thalassaemia patients

This exploratory study assessed apoptosis in peripheral blood leucocytes (PBL) from β-thalassaemia patients receiving chronic transfusions and chelation therapy (deferasirox or deferoxamine) at baseline, 1, 6, and 12 months. At baseline, thalassaemic PBLs presented 50% greater levels of Bax (BAX), 7...

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Publicado en:Br J Haematol
Autores principales: Walter, Patrick B., Porter, John, Evans, Patricia, Kwiatkowski, Janet L., Neufeld, Ellis J., Coates, Thomas, Giardina, Patricia J., Grady, Robert W., Vichinsky, Elliott, Olivieri, Nancy, Trachtenberg, Felicia, Alberti, Daniele, Fung, Ellen, Ames, Bruce, Higa, Annie, Harmatz, Paul
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4597914/
https://ncbi.nlm.nih.gov/pubmed/23216540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bjh.12076
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