Suppression of inducible cyclooxygenase 2 gene transcription by aspirin and sodium salicylate

The pharmacological action of salicylate cannot be explained by its inhibition of cyclooxygenase (COX) activity. In this report, the effects of aspirin and sodium salicylate on COX-2 expressions in human umbilical vein endothelial cells and foreskin fibroblasts were evaluated. Aspirin and sodium sal...

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Bibliographic Details
Main Authors: Xu, Xiao-Ming, Sansores-Garcia, Leticia, Chen, Xian-Ming, Matijevic-Aleksic, Nevenka, Du, Min, Wu, Kenneth K.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 1999
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC21857/
https://ncbi.nlm.nih.gov/pubmed/10220459
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