Tissue Transglutaminase Does Not Contribute to the Formation of Mutant Huntingtin Aggregates

The cause of Huntington's disease (HD) is a pathological expansion of the polyglutamine domain within the NH(2)-terminal region of huntingtin. Neuronal intranuclear inclusions and cytoplasmic aggregates composed of the mutant huntingtin within certain neuronal populations are a characteristic h...

Full description

Saved in:
Bibliographic Details
Main Authors: Chun, Wanjoo, Lesort, Mathieu, Tucholski, Janusz, Ross, Christopher A., Johnson, Gail V.W.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2001
Subjects:
Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2185516/
https://ncbi.nlm.nih.gov/pubmed/11285271
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items