Tissue Transglutaminase Does Not Contribute to the Formation of Mutant Huntingtin Aggregates

The cause of Huntington's disease (HD) is a pathological expansion of the polyglutamine domain within the NH(2)-terminal region of huntingtin. Neuronal intranuclear inclusions and cytoplasmic aggregates composed of the mutant huntingtin within certain neuronal populations are a characteristic h...

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Hauptverfasser: Chun, Wanjoo, Lesort, Mathieu, Tucholski, Janusz, Ross, Christopher A., Johnson, Gail V.W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2001
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2185516/
https://ncbi.nlm.nih.gov/pubmed/11285271
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