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In vitro maturation of immature thymocytes into immunocompetent T cells in the absence of direct thymic influence

Peanut lectin (PNL) binds to a majority of mouse thymocytes (Thc) in suspension. By using cell affinity chromatography on a column of anti-PNL antibody, Thc populations at least 96 percent pure in PNL + or - cells, as judged by immunofluorescence, were obtained. PNL(+) cells are rich in Thy 1 and po...

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Bibliographic Details
Main Authors: Irle, C, Piguet, P-F, Vassalli, P
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1978
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2184919/
https://ncbi.nlm.nih.gov/pubmed/78962
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