Hypermutation in derepressed operons of Escherichia coli K12
This article presents evidence that starvation for leucine in an Escherichia coli auxotroph triggers metabolic activities that specifically target the leu operon for derepression, increased rates of transcription, and mutation. Derepression of the leu operon was a prerequisite for its activation by...
Gardado en:
| Publicado en: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
1999
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21821/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10220423/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.9.5089 |
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