Hypermutation in derepressed operons of Escherichia coli K12

This article presents evidence that starvation for leucine in an Escherichia coli auxotroph triggers metabolic activities that specifically target the leu operon for derepression, increased rates of transcription, and mutation. Derepression of the leu operon was a prerequisite for its activation by...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Wright, Barbara E., Longacre, Angelika, Reimers, Jacqueline M.
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1999
Sujets:	Biological Sciences
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21821/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10220423/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.9.5089
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