Synoviolin/Hrd1, an E3 ubiquitin ligase, as a novel pathogenic factor for arthropathy

Rheumatoid arthritis (RA) is one of the most critical articular diseases with synovial hyperplasia followed by impairment of quality of life. However, the mechanism(s) that regulates synovial cell outgrowth is not fully understood. To clarify its mechanism(s), we carried out immunoscreening by using...

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Autori principali: Amano, Tetsuya, Yamasaki, Satoshi, Yagishita, Naoko, Tsuchimochi, Kaneyuki, Shin, Hiroshi, Kawahara, Ko-ichi, Aratani, Satoko, Fujita, Hidetoshi, Zhang, Lei, Ikeda, Rie, Fujii, Ryoji, Miura, Naoki, Komiya, Setsuro, Nishioka, Kusuki, Maruyama, Ikuro, Fukamizu, Akiyoshi, Nakajima, Toshihiro
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2003
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Research Papers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC218080/
https://ncbi.nlm.nih.gov/pubmed/12975321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1096603
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