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Enrichment of antigen-specific B lymphocytes by the direct removal of B cells not bearing specificity for the antigen

Antigen-specific B cells (ASC) were purified from other B cells by prior incubation with specific antigen followed by rosetting with erythrocytes conjugated with anti-mouse Ig and sedimenting on Ficoll- Isopaque. This procedure allowed the removal of most of the B cells, while those speicifc for the...

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Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1977
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2180762/
https://ncbi.nlm.nih.gov/pubmed/69002
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