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A requirement for antigen-specific helper T cells in the generation of cytotoxic T cells from thymocyte precursors

Thymocytes cultured with irradiated, allogeneic stimulator cells yield no cytotoxic effector cells after a period in culture. If, however, a population of irradiated spleen cells syngeneic to the responder cells are added to these cultures, cytotoxicity is generated. The helper activity present in t...

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Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1977
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2180707/
https://ncbi.nlm.nih.gov/pubmed/233910
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