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A requirement for antigen-specific helper T cells in the generation of cytotoxic T cells from thymocyte precursors
Thymocytes cultured with irradiated, allogeneic stimulator cells yield no cytotoxic effector cells after a period in culture. If, however, a population of irradiated spleen cells syngeneic to the responder cells are added to these cultures, cytotoxicity is generated. The helper activity present in t...
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| Format: | Artigo |
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| Language: | Inglês |
| Published: |
The Rockefeller University Press
1977
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2180707/ https://ncbi.nlm.nih.gov/pubmed/233910 |
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