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Helper T cells are required for the polyclonal stimulation of cytotoxic T cells by concanavalin A

Concanavalin A stimulation of T-cell cytotoxicity has been shown to be absolutely dependent on helper T-cell collaboration. Thymocytes stimulated with ConA do not differentiate to yield cytotoxic effector cells. However, thymocytes cocultured with irradiated spleen cells as helpers and ConA yield hi...

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Detalles Bibliográficos
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 1977
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2180654/
https://ncbi.nlm.nih.gov/pubmed/300781
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