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Helper T cells are required for the polyclonal stimulation of cytotoxic T cells by concanavalin A
Concanavalin A stimulation of T-cell cytotoxicity has been shown to be absolutely dependent on helper T-cell collaboration. Thymocytes stimulated with ConA do not differentiate to yield cytotoxic effector cells. However, thymocytes cocultured with irradiated spleen cells as helpers and ConA yield hi...
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| Format: | Artigo |
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| Language: | Inglês |
| Published: |
The Rockefeller University Press
1977
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2180654/ https://ncbi.nlm.nih.gov/pubmed/300781 |
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