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STUDIES IN PORPHYRIA : II. EVIDENCE FOR A DEFICIENCY OF STEROID Δ(4)-5α-REDUCTASE ACTIVITY IN ACUTE INTERMITTENT PORPHYRIA
Patients with the genetic liver disease, acute intermittent porphyria (AIP), have a defect in the reductive transformation of steroid hormones that is manifest by the disproportionate generation of 5β-steroid metabolites from precursor hormones. 5β-steroid metabolites were earlier shown to be potent...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Rockefeller University Press
1973
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2180579/ https://ncbi.nlm.nih.gov/pubmed/4270345 |
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