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PTHrP increases xenograft growth and promotes integrin α6β4 expression and Akt activation in colon cancer
Parathyroid hormone-related protein (PTHrP) is expressed by human colon cancer tissue and cell lines. Expression of PTHrP and phosphatidylinositol 3-kinase (PI3-K) pathway components correlates with the severity of colon carcinoma. Here we observed a positive effect of endogenous PTHrP on LoVo (huma...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2007
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2180421/ https://ncbi.nlm.nih.gov/pubmed/17964713 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2007.09.010 |
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