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PTHrP increases xenograft growth and promotes integrin α6β4 expression and Akt activation in colon cancer

Parathyroid hormone-related protein (PTHrP) is expressed by human colon cancer tissue and cell lines. Expression of PTHrP and phosphatidylinositol 3-kinase (PI3-K) pathway components correlates with the severity of colon carcinoma. Here we observed a positive effect of endogenous PTHrP on LoVo (huma...

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Bibliografische gegevens
Hoofdauteurs: Shen, Xiaoli, Rychahou, Piotr G., Evers, B. Mark, Falzon, Miriam
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2007
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2180421/
https://ncbi.nlm.nih.gov/pubmed/17964713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2007.09.010
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