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STUDIES ON THE MECHANISM OF THE FORMATION OF THE PENICILLIN ANTIGEN : III. THE N-(D-α-BENZYLPENICILLOYL) GROUP AS AN ANTIGENIC DETERMINANT RESPONSIBLE FOR HYPERSENSITIVITY TO PENICILLIN G

An excess of D-benzylpenicillenic acid (BPE) was reacted with human γ-globulin, human serum albumin, gelatin, and poly-L-lysine in aqueous solution buffered at pH 7.5–8.0. Under these conditions, BPE reacted predominantly with lysine ε-amino groups of the proteins to form the mixture of diastereomer...

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Detalhes bibliográficos
Main Authors: Levine, Bernard B., Ovary, Zoltan
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1961
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2180410/
https://ncbi.nlm.nih.gov/pubmed/14464604
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