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FoxO Tumor Suppressors and BCR-ABL-Induced Leukemia: A Matter of Evasion of Apoptosis

Numerous studies have revealed that the BCR-ABL oncoprotein abnormally engages a multitude of signaling pathways, some of which may be important for its leukemogenic properties. Central to this has been the determination that the tyrosine kinase function of BCR-ABL is mainly responsible for its tran...

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Detalhes bibliográficos
Main Authors: Jagani, Zainab, Singh, Amrik, Khosravi-Far, Roya
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2180393/
https://ncbi.nlm.nih.gov/pubmed/17980712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbcan.2007.10.003
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