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Delay-Dependent Working Memory Impairment in Young-Adult and Aged 5-HT1BKO Mice as Assessed in a Radial-Arm Water Maze

Serotonin (5-HT) plays a modulatory role in mnemonic functions, especially by interacting with the cholinergic system. The 5-HT1B receptor is a key target of this interaction. The 5-HT1B receptor knockout mice were found previously to exhibit a facilitation in hippocampal-dependent spatial reference...

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Detalhes bibliográficos
Main Authors: Wolff, Mathieu, Benhassine, Narimane, Costet, Pierre, Hen, René, Segu, Louis, Buhot, Marie-Christine
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC218006/
https://ncbi.nlm.nih.gov/pubmed/14557613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/lm.60103
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