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Signal transfer from rhodopsin to the G-protein: Evidence for a two-site sequential fit mechanism

Photoactivation of the retinal photoreceptor rhodopsin proceeds through a cascade of intermediates, resulting in protein–protein interactions catalyzing the activation of the G-protein transducin (Gt). Using stabilization and photoregeneration of the receptor’s signaling state and Gt activation assa...

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Autori principali: Kisselev, Oleg G., Meyer, Christoph K., Heck, Martin, Ernst, Oliver P., Hofmann, Klaus Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC21788/
https://ncbi.nlm.nih.gov/pubmed/10220390
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