Variable Prostaglandin E(2) Resistance in Fibroblasts from Patients with Usual Interstitial Pneumonia

Rationale: Prostaglandin (PG) E(2), a cyclooxygenase-derived lipid mediator, is a potent down-regulator of fibroblast activation in normal lung fibroblasts. Although fibroblasts from patients with idiopathic pulmonary fibrosis are known to exhibit a defect in PGE(2) synthesis, there is little inform...

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Main Authors: Huang, Steven K., Wettlaufer, Scott H., Hogaboam, Cory M., Flaherty, Kevin R., Martinez, Fernando J., Myers, Jeffrey L., Colby, Thomas V., Travis, William D., Toews, Galen B., Peters-Golden, Marc
Format: Artigo
Jezik:Inglês
Izdano: American Thoracic Society 2008
Teme:
E. Interstitial Lung Disease
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2176116/
https://ncbi.nlm.nih.gov/pubmed/17916807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200706-963OC
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