Beryllium-Induced TNF-α Production Is Transcription-Dependent in Chronic Beryllium Disease

Beryllium (Be)-antigen presentation to Be-specific CD4(+) T cells from the lungs of patients with chronic beryllium disease (CBD) results in T cell proliferation and TNF-α secretion. We tested the hypothesis that Be-induced, CBD bronchoalveolar lavage (BAL) T cell, transcription-dependent, TNF-α sec...

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Detalhes bibliográficos
Main Authors: Sawyer, Richard T., Fontenot, Andrew P., Barnes, Tristan A., Parsons, Charles E., Tooker, Brian C., Maier, Lisa A., Gillespie, May M., Gottschall, E. Brigitte, Silveira, Lori, Hagman, James, Newman, Lee S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2007
Assuntos:
Translational Reviews
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2176111/
https://ncbi.nlm.nih.gov/pubmed/16980557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2006-0021TR
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