4G/5G Plasminogen Activator Inhibitor-1 Polymorphisms and Haplotypes Are Associated with Pneumonia

Rationale: Plasminogen activator inhibitor (PAI)-1 inhibits urokinase and tissue plasminogen activator, required for host response to infection. Whether variation within the PAI-1 gene is associated with increased susceptibility to infection is unknown. Objectives: To ascertain the role of the 4G/5G...

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Hlavní autoři: Yende, Sachin, Angus, Derek C., Ding, Jingzhong, Newman, Anne B., Kellum, John A., Li, Rongling, Ferrell, Robert E., Zmuda, Joseph, Kritchevsky, Stephen B., Harris, Tamara B., Garcia, Melissa, Yaffe, Kristine, Wunderink, Richard G.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2007
Témata:
G. Pulmonary Infections
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2176102/
https://ncbi.nlm.nih.gov/pubmed/17761618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200605-644OC
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