4G/5G Plasminogen Activator Inhibitor-1 Polymorphisms and Haplotypes Are Associated with Pneumonia

Rationale: Plasminogen activator inhibitor (PAI)-1 inhibits urokinase and tissue plasminogen activator, required for host response to infection. Whether variation within the PAI-1 gene is associated with increased susceptibility to infection is unknown. Objectives: To ascertain the role of the 4G/5G...

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Detalhes bibliográficos
Main Authors: Yende, Sachin, Angus, Derek C., Ding, Jingzhong, Newman, Anne B., Kellum, John A., Li, Rongling, Ferrell, Robert E., Zmuda, Joseph, Kritchevsky, Stephen B., Harris, Tamara B., Garcia, Melissa, Yaffe, Kristine, Wunderink, Richard G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2007
Assuntos:
G. Pulmonary Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2176102/
https://ncbi.nlm.nih.gov/pubmed/17761618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200605-644OC
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