4G/5G Plasminogen Activator Inhibitor-1 Polymorphisms and Haplotypes Are Associated with Pneumonia

Rationale: Plasminogen activator inhibitor (PAI)-1 inhibits urokinase and tissue plasminogen activator, required for host response to infection. Whether variation within the PAI-1 gene is associated with increased susceptibility to infection is unknown. Objectives: To ascertain the role of the 4G/5G...

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Bibliographische Detailangaben
Hauptverfasser: Yende, Sachin, Angus, Derek C., Ding, Jingzhong, Newman, Anne B., Kellum, John A., Li, Rongling, Ferrell, Robert E., Zmuda, Joseph, Kritchevsky, Stephen B., Harris, Tamara B., Garcia, Melissa, Yaffe, Kristine, Wunderink, Richard G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Thoracic Society 2007
Schlagworte:
G. Pulmonary Infections
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2176102/
https://ncbi.nlm.nih.gov/pubmed/17761618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200605-644OC
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