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Alcohol Ingestion by Donors Amplifies Experimental Airway Disease after Heterotopic Transplantation

Rationale: Obliterative bronchiolitis (OB) after lung transplantation is triggered by alloimmunity, but is ultimately mediated by transforming growth factor (TGF)-β(1)–dependent airway fibrosis. Objectives: Chronic alcohol use increases TGF-β(1) expression and renders the lung susceptible to injury....

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Mitchell, Patrick O., Guidot, David M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Thoracic Society 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2176096/
https://ncbi.nlm.nih.gov/pubmed/17717204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200702-255OC
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