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Alcohol Ingestion by Donors Amplifies Experimental Airway Disease after Heterotopic Transplantation
Rationale: Obliterative bronchiolitis (OB) after lung transplantation is triggered by alloimmunity, but is ultimately mediated by transforming growth factor (TGF)-β(1)–dependent airway fibrosis. Objectives: Chronic alcohol use increases TGF-β(1) expression and renders the lung susceptible to injury....
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Thoracic Society
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2176096/ https://ncbi.nlm.nih.gov/pubmed/17717204 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200702-255OC |
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