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Use-dependent block of Na+ currents by mexiletine at the single channel level in guinea-pig ventricular myocytes.

1. The mechanism of use-dependent block of Na+ current by mexiletine was studied at the single channel level in guinea-pig ventricular myocytes by the patch-clamp techniques. All experiments were performed using stimulation protocols to enable us to analyze the strict dependence of changes in channe...

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Bibliografiska uppgifter
Huvudupphovsmän: Sunami, A., Fan, Z., Sawanobori, T., Hiraoka, M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 1993
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175969/
https://ncbi.nlm.nih.gov/pubmed/8220878
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