Thermodynamics of antagonist binding to rat muscarinic M2 receptors: antimuscarinics of the pridinol, sila-pridinol, diphenidol and sila-diphenidol type.

1. We studied the effect of temperature on the binding to rat heart M2 muscarinic receptors of antagonists related to the carbon/silicon pairs pridinol/sila-pridinol and diphenidol/sila-diphenidol (including three germanium compounds) and six structurally related pairs of enantiomers [(R)- and (S)-p...

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Main Authors: Waelbroeck, M., Camus, J., Tastenoy, M., Lambrecht, G., Mutschler, E., Kropfgans, M., Sperlich, J., Wiesenberger, F., Tacke, R., Christophe, J.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 1993
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175680/
https://ncbi.nlm.nih.gov/pubmed/8102927
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