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Stereoselective recognition of the enantiomers of phenglutarimide and of six related compounds by four muscarinic receptor subtypes.

1. We have compared the binding properties of the enantiomers of phenglutarimide (1) and of six related compounds to M1 receptors in NB-OK-1 cells, M2 receptors in rat heart, M3 receptors in rat pancreas and the M4 receptors of rat striatum, with their functional (antimuscarinic) properties in rabbi...

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Autors principals: Waelbroeck, M., Lazareno, S., Pfaff, O., Friebe, T., Tastenoy, M., Mutschler, E., Lambrecht, G.
Format: Artigo
Idioma:Inglês
Publicat: 1996
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1915812/
https://ncbi.nlm.nih.gov/pubmed/8968538
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