Selective MPP+ uptake into synaptic dopamine vesicles: possible involvement in MPTP neurotoxicity.

1. In the present study we provide evidence for a saturable, Mg2+/ATP- and temperature-dependent, tetrabenazine-, dopamine-, and amphetamine-sensitive uptake of 1-methyl-4-phenylpyridinium ion (MPP+) in synaptic vesicles from mouse striatum. 2. Similarity in the properties of the vesicular uptake su...

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Main Authors: Del Zompo, M., Piccardi, M. P., Ruiu, S., Quartu, M., Gessa, G. L., Vaccari, A.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 1993
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175677/
https://ncbi.nlm.nih.gov/pubmed/8102929
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