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Protection by the NDI1 Gene against Neurodegeneration in a Rotenone Rat Model of Parkinson's Disease
It is widely recognized that mitochondrial dysfunction, most notably defects in the NADH-quinone oxidoreductase (complex I), is closely related to the etiology of sporadic Parkinson's disease (PD). In fact, rotenone, a complex I inhibitor, has been used for establishing PD models both in vitro...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2175531/ https://ncbi.nlm.nih.gov/pubmed/18197244 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001433 |
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