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Conserved amino acids in each subunit of the heteroligomeric tRNA m(1)A58 Mtase from Saccharomyces cerevisiae contribute to tRNA binding

In Saccharomyces cerevisiae, a two-subunit methyltransferase (Mtase) encoded by the essential genes TRM6 and TRM61 is responsible for the formation of 1-methyladenosine, a modified nucleoside found at position 58 in tRNA that is critical for the stability of [Formula: see text]. The crystal structur...

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Detalhes bibliográficos
Main Authors: Ozanick, Sarah G., Bujnicki, Janusz M., Sem, Daniel S., Anderson, James T.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2007
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175304/
https://ncbi.nlm.nih.gov/pubmed/17932071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm574
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