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In Vivo Importance of Actin Nucleotide Exchange Catalyzed by Profilin

The actin monomer-binding protein, profilin, influences the dynamics of actin filaments in vitro by suppressing nucleation, enhancing nucleotide exchange on actin, and promoting barbed-end assembly. Profilin may also link signaling pathways to actin cytoskeleton organization by binding to the phosph...

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Auteurs principaux: Wolven, Amy K., Belmont, Lisa D., Mahoney, Nicole M., Almo, Steven C., Drubin, David G.
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2000
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175289/
https://ncbi.nlm.nih.gov/pubmed/10953013
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