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Increased spinal dynorphin contributes to chronic nicotine-induced mechanical hypersensitivity in the rat
Chronic nicotine administration has been shown previously to produce mechanical hypersensitivity in the rat although the mechanism of this effect is unknown. Rats treated with chronic systemic nicotine 3.6 or 8.6 mg/kg/day for 14-21 days displayed mechanical hypersensitivity coincident with an incre...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2175268/ https://ncbi.nlm.nih.gov/pubmed/17597300 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2007.06.002 |
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