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Molecular mechanism for analgesia involving specific antagonism of α9α10 nicotinic acetylcholine receptors

α9α10 nicotinic acetylcholine receptors (nAChRs) have been identified in a variety of tissues including lymphocytes and dorsal root ganglia; except in the case of the auditory system, the function of α9α10 nAChRs is not known. Here we show that selective block (rather than stimulation) of α9α10 nACh...

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Détails bibliographiques
Auteurs principaux: Vincler, Michelle, Wittenauer, Shannon, Parker, Renee, Ellison, Michael, Olivera, Baldomero M., McIntosh, J. Michael
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635975/
https://ncbi.nlm.nih.gov/pubmed/17101979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0608715103
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