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The Transcriptional Coactivator Cbp Interacts with β-Catenin to Activate Gene Expression

β-Catenin plays a pivotal role in the transcriptional activation of Wnt-responsive genes by binding to TCF/LEF transcription factors. Although it has been suggested that the COOH-terminal region of β-catenin functions as an activation domain, the mechanisms of activation remain unclear. To screen fo...

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Autori principali: Takemaru, Ken-Ichi, Moon, Randall T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175158/
https://ncbi.nlm.nih.gov/pubmed/10769018
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