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Plasmin-Sensitive Dibasic Sequences in the Third Fibronectin-like Domain of L1–Cell Adhesion Molecule (CAM) Facilitate Homomultimerization and Concomitant Integrin Recruitment

L1 is a multidomain transmembrane neural recognition molecule essential for neurohistogenesis. While moieties in the immunoglobulin-like domains of L1 have been implicated in both heterophilic and homophilic binding, the function of the fibronectin (FN)-like repeats remains largely unresolved. Here,...

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Autori principali: Silletti, Steve, Mei, Fang, Sheppard, Dean, Montgomery, Anthony M.P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175144/
https://ncbi.nlm.nih.gov/pubmed/10871287
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