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Phosphorylation of Connexin43 on Serine368 by Protein Kinase C Regulates Gap Junctional Communication

Phorbol esters (e.g., TPA) activate protein kinase C (PKC), increase connexin43 (Cx43) phosphorylation, and decrease cell–cell communication via gap junctions in many cell types. We asked whether PKC directly phosphorylates and regulates Cx43. Rat epithelial T51B cells metabolically labeled with (32...

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Bibliografische gegevens
Hoofdauteurs: Lampe, Paul D., TenBroek, Erica M., Burt, Janis M., Kurata, Wendy E., Johnson, Ross G., Lau, Alan F.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2000
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175134/
https://ncbi.nlm.nih.gov/pubmed/10871288
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