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Phosphorylation of Connexin43 on Serine368 by Protein Kinase C Regulates Gap Junctional Communication

Phorbol esters (e.g., TPA) activate protein kinase C (PKC), increase connexin43 (Cx43) phosphorylation, and decrease cell–cell communication via gap junctions in many cell types. We asked whether PKC directly phosphorylates and regulates Cx43. Rat epithelial T51B cells metabolically labeled with (32...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lampe, Paul D., TenBroek, Erica M., Burt, Janis M., Kurata, Wendy E., Johnson, Ross G., Lau, Alan F.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Rockefeller University Press 2000
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175134/
https://ncbi.nlm.nih.gov/pubmed/10871288
Tagiau: Ychwanegu Tag
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